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Antigenic Specificity | Human THRA / THR Alpha |
Clone | polyclonal |
Host Species | Goat |
Reactive Species | Gibbon, bovine, dog, gorilla, hamster, horse, human, monkey, mouse, porcine, rabbit, rat, sheep |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 0.05 mg |
Concentration | 0.5 mg/ml |
Applications | Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Human THRA. This antibody is expected to recognize both reported isoforms (NP_955366.1; NP_003241.2). This antibody is not expected to cross-react to THRB. Thyroid hormone receptor alpha (TR alpha), a NR1 Thyroid Hormone-Like Receptor, mediates the diverse actions of thyroid hormone in development, differentiation, and metabolism. Four protein isoforms are encoded by the same TR alpha genomic locus: TR alpha1 (410 aa) (Nakai et al. 1988), TR alpha2 (490 aa) (Nakai et al. 1988), TR deltaalpha1 (~154 aa), and TR deltaalpha2 (~237 aa); however, only TR alpha1 is able to bind the ligand (Lazar et al. 1988). |
Immunogen | Immunogen Description: Synthetic peptide C-KEEMIRSLQQRP from an internal region of human THRA (NP_955366.1; NP_003241.2). |
Other Names | [THRA / THR Alpha (Internal) IHC-plus; THRA; AR7; C-ERBA-1; C-erbaalpha; EAR-7.1/EAR-7.2; ERB-T-1; ERBA1; EAR-7; ERBA-related 7; HTR alpha 1; HTR alpha 2; THRA1; Thyroid hormone receptor alpha; T3R; Tralpha2; Triiodothyronine receptor; V-erbA-related protein 7; Thyroid hormone receptor; Human THRA; THR Alpha], [THRA; THRA; AR7; EAR7; ERBA; CHNG6; ERBA1; NR1A1; THRA1; THRA2; ERB-T-1; c-ERBA-1; EAR7; ERBA1; NR1A1; THRA1; THRA2; EAR-7] |
Gene, Accession # | [THRA], Gene ID: 7067, NCBI: NP_003241.2, UniProt: P10827 |
Catalog # | MBS242765 |
Price | $530 |
Order / More Info | Human THRA / THR Alpha Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |