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Antigenic Specificity | EpoR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkey |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunofluorescence (IF), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: EpoR Polyclonal Antibody detects endogenous levels of EpoR protein. EPOR encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. |
Immunogen | Immunogen: Synthesized peptide derived from human EpoR around the non-phosphorylation site of Y368 |
Other Names | [Rabbit EpoR; EPOR; Erythropoietin receptor; EPO-R] |
Gene, Accession # | [EPOR], Gene ID: 2057, NCBI: NP_000112.1, UniProt: P19235 |
Catalog # | MBS9704781 |
Price | $130, $220, $325 |
Order / More Info | EpoR Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |