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Antigenic Specificity | IFNL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 0.05 mL, 0.1 mL |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression. |
Immunogen | Immunogen: Recombinant human Interferon lambda-1 protein (20-200aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-67642 / sc-67643 / sc-130787 |
Other Names | [IFN-lambda-1; Cytokine Zcyto21; Interleukin-29; IL-29; IFNL1; IL29; ZCYTO21], [IFNL1; IFNL1; IL29; IL-29; IL29; ZCYTO21; IFN-lambda-1; IL-29] |
Gene, Accession # | [IFNL1], Gene ID: 282618, NCBI: NP_742152.1, UniProt: Q8IU54 |
Catalog # | MBS1497895 |
Price | $120, $160 |
Order / More Info | IFNL1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |