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Antigenic Specificity | APOE (C-term), 263-292 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: monkey, rabbit) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This APOE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 263-292 amino acids from the C-terminal region of human APOE. Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III),in which increased plasm |
Immunogen | n/a |
Other Names | [Apolipoprotein E; Apo-E; APOE] |
Gene, Accession # | [APOE], Gene ID: 348, NCBI: NP_000032.1, UniProt: P02649 |
Catalog # | MBS9214750 |
Price | $165, $370 |
Order / More Info | APOE (C-term), 263-292 Antibody from MYBIOSOURCE INC. |
Product Specific References | Wood,K.C., Appl Physiol Nutr Metab 33 (4), 761-768 (2008) Pemberton,L., (er) HIV Med. (2008) In press Sundermann,E.E., (er) Horm Behav (2008) In press Christensen,H.,(er) BMC Geriatr 8, 14 (2008) |