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Antigenic Specificity | Phospho-KDR (Y1175) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This KDR Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1175 of human KDR. Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. |
Immunogen | n/a |
Other Names | [Vascular endothelial growth factor receptor 2; VEGFR-2; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1; CD309; KDR; FLK1; VEGFR2] |
Gene, Accession # | [KDR], Gene ID: 3791, NCBI: NP_002244.1, UniProt: P35968 |
Catalog # | MBS9207861 |
Price | $165, $370 |
Order / More Info | Phospho-KDR (Y1175) Antibody from MYBIOSOURCE INC. |
Product Specific References | Huang, D., et al. Cancer Res. 70(3):1053-1062(2010) Sentilhes, L., et al. J. Neuropathol. Exp. Neurol. 69(2):111-128(2010) Lamalice, L., et al. J. Biol. Chem. 281(45):34009-34020(2006) |