Phospho-IRS-1 (Ser307) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Phospho-IRS-1 (Ser307) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat, monkey |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemisty (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Phospho-IRS-1 (Ser307) antibody detects endogenous levels of IRS-1 only when phosphorylated at Serine 307. Description: IRS-1 is an adaptor protein that is one of the major substrates of the insulin receptor kinase. Contains multiple tyrosine phosphorylation motifs that serve as docking sites for SH2-domain-containing proteins including phosphatidylinositol 3-kinase p85 subunit and GRB-2.Function: May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similar |
| Immunogen | Immunogen: A synthesized peptide derived from human IRS-1 around the phosphorylation site of Serine 307 Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (100%), Zebrafish (82%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
| Other Names | [HIRS 1; HIRS1; Insulin receptor substrate 1; IRS 1; IRS-1; IRS1; IRS1_HUMAN; OTTHUMP00000164234] |
| Gene, Accession # | [IRS-1], Gene ID: 3667, NCBI: NP_005535.1, UniProt: P35568 |
| Catalog # | MBS9601043 |
| Price | $240, $280 |
| Order / More Info | Phospho-IRS-1 (Ser307) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Geng S, Zhu W, Wang S, Xie C, Li X, Wu J, Li Y, Chen Y, Wang X, Meng Y, Zhang Q, Chen J, Zhong C; Journal: Biochem Biophys Res Commun. P53 modulates hepatic insulin sensitivity through NF-kB and p38/ERK MAPK pathways. Geng S, Wang S, Zhu W, Xie C, Li X, Wu J, Zhu J, Jiang Y, Yang X, Li Y, Chen Y, Wang X, Meng Y, Zhong C; Journal: Biomed Pharmacother. Curcumin suppresses JNK pathway to attenuate BPA-induced insulin resistance in LO2 cells. Geng S, Wang S, Zhu W, Xie C, Li X, Wu J, Zhu J, Jiang Y, Yang X, Li Y, Chen Y, Wang X, Meng Y, Zhu M, Wu R, Huang C, Zhong C; Journal: Toxicol Lett. Curcumin attenuates BPA-induced insulin resistance in HepG2 cells through suppression of JNK/p38 pathways. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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