Beta2-adrenoceptor, Human Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Beta2-adrenoceptor, Human |
| Clone | 6H8 |
| Host Species | Mouse |
| Reactive Species | reactivity: human. cross reactivity: guinea pig, rat |
| Isotype | IgG1 |
| Format | unconjugated |
| Size | 0.1 mg |
| Concentration | n/a |
| Applications | Flow Cytometry (FC/FACS), FS, Immunoassay (IA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Product Description: The monoclonal antibody 6H8 recognizes human beta2-adrenoceptor. The b -adrenoceptors can be divided into b1, b2, b3 and b4-adrenoceptors defined in terms of agonist potencies, b2-adrenoceptors displayed a higher selectivity for nor-adrenaline than for adrenaline. B2-receptors are mainly postsynaptic and are located on a number of tissues including blood vessels, bronchi, GIT, skeletal muscle, liver and mast cell. Activation results in vasodilatation, bronchodilation, relaxation of the GIT, glycogenolysis in the liver, tremor in skeletal muscle and inhibition of histamine release from mast cells.- Transduction is via G-proteins coupled to the intracellular second messenger adenylate cyclase. B-receptors are positively c |
| Immunogen | Immunogen: Free peptide Beta2-H19C |
| Other Names | n/a |
| Gene, Accession # | n/a |
| Catalog # | MBS584424 |
| Price | $555 |
| Order / More Info | Beta2-adrenoceptor, Human Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Lebesgue, D et al; An agonist-like monoclonal antibody against the human beta2-adrenoceptor. Eur J Pharmacol 1998, 348: 123. 2. Mijares, A et al; From agonist to antagonist: Fab fragments of an agonistic-like monoclonal anti-beta2-adrenoceptor antibody behaves as antagonists. Mol Pharmacol 2000, 58: 373. |
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MYBIOSOURCE INC.
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