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Antigenic Specificity | LFC |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | mouse |
Isotype | n/a |
Format | ammonium sulfate precipitate |
Size | 0.25 mg |
Concentration | n/a |
Applications | Western Blot (WB), Immunoprecipitation (IP, Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Lfc is a 118 kDa protein discovered in a screen for oncogenes in NIH 3T3 cells. Lfc is a signaling protein related to Lbc and is part of the Dbl family of proteins. Lfc is a guanine-nucleotide exchange factor (GEF) for the Rho family of small GTPases. Lfc has also been shown to be upstream of the serine-threonine kinase JNK. Lfc has also been shown to mediate the activation of the Rac signaling pathway. |
Immunogen | Immunogen: Antibody developed using protein corresponding to amino acids 2 to 447 of the Lfc protein fused to GST. |
Other Names | [Rho guanine nucleotide exchange factor 2; ARHGEF2], [Arhgef2; Arhgef2; GEF; Lfc; P40; GEFH1; LFP40; Lbcl1; GEF-H1; AA408978; mKIAA0651; Kiaa0651; Lbcl1; Lfc; GEF-H1] |
Gene, Accession # | [LFC], Gene ID: 16800, NCBI: NP_001185840.1, UniProt: Q60875 |
Catalog # | MBS395796 |
Price | $340 |
Order / More Info | LFC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |