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Antigenic Specificity | Cofilin 1 (Ser-3), phospho-specific |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, rat, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | ELISA, Western Blot |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This antibody was cross-adsorbed to unphosphorylated Coflin 1 peptide then affinity purified using phospho-Cofilin 1 (Ser-3) peptide (without carrier). The antibody detects a 19 kDa* protein corresponding to the molecular mass of phosphorylated Cofilin 1 on SDS-PAGE immunoblots of Jurkat cells. This band can be removed by lambda phosphatase treatment. Members of the ADF/cofilin (AC) family are actin-severing proteins that regulate actin remodeling during cellular events such as cell migration, cytokinesis, phagocytosis, endocytosis, axon development, and immune cell activation. In mammals, there are three members of the AC family, muscle-specific cofilin (Cofilin 2), non-muscle cofilin (Cofilin 1), and ADF. In humans, cofilin 1 and ADF have |
Immunogen | Immunogen: A synthetic phospho-peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 3 in human Cofilin 1. This sequence has 100% homology with similar regions of rat and mouse Cofilin 1, and has two amino acid differences from human Cofilin 2. |
Other Names | [p18; 18 kDa phosphoprotein], [CFL1; CFL1; CFL; CFL] |
Gene, Accession # | Gene ID: 1072, NCBI: P23528.3, UniProt: P23528 |
Catalog # | MBS472016 |
Price | $385 |
Order / More Info | Cofilin 1 (Ser-3), phospho-specific Antibody from MYBIOSOURCE INC. |
Product Specific References | • Bamburg, J.R. (1999). Annu Rev Cell Dev Biol. 15:185• Maciver, S.K. & Hussey, P.J. (2002). Genome Biol. 3(5): 3007 |