Cofilin 1 (Ser-3), phospho-specific Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCofilin 1 (Ser-3), phospho-specific
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsELISA, Western Blot
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DescriptionThis antibody was cross-adsorbed to unphosphorylated Coflin 1 peptide then affinity purified using phospho-Cofilin 1 (Ser-3) peptide (without carrier). The antibody detects a 19 kDa* protein corresponding to the molecular mass of phosphorylated Cofilin 1 on SDS-PAGE immunoblots of Jurkat cells. This band can be removed by lambda phosphatase treatment. Members of the ADF/cofilin (AC) family are actin-severing proteins that regulate actin remodeling during cellular events such as cell migration, cytokinesis, phagocytosis, endocytosis, axon development, and immune cell activation. In mammals, there are three members of the AC family, muscle-specific cofilin (Cofilin 2), non-muscle cofilin (Cofilin 1), and ADF. In humans, cofilin 1 and ADF have
ImmunogenImmunogen: A synthetic phospho-peptide (coupled to KLH) corresponding to amino acid residues surrounding serine 3 in human Cofilin 1. This sequence has 100% homology with similar regions of rat and mouse Cofilin 1, and has two amino acid differences from human Cofilin 2.
Other Names[p18; 18 kDa phosphoprotein], [CFL1; CFL1; CFL; CFL]
Gene, Accession #Gene ID: 1072, NCBI: P23528.3, UniProt: P23528
Catalog #MBS472016
Price$385
Order / More InfoCofilin 1 (Ser-3), phospho-specific Antibody from MYBIOSOURCE INC.
Product Specific References• Bamburg, J.R. (1999). Annu Rev Cell Dev Biol. 15:185• Maciver, S.K. & Hussey, P.J. (2002). Genome Biol. 3(5): 3007
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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