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Antigenic Specificity | FLCN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, monkeypredicted: porcine, bovine, rabbit, dog, chicken, Xenopus |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: FLCN Antibody detects endogenous levels of FLCN. Description: May be a tumor suppressor. May be involved in energy and/or nutrient sensing through the AMPK and mTOR signaling pathways. May regulate phosphorylation of RPS6KB1.Post Translational Modifications: Phosphorylated. Several different phosphorylated forms exist.Subunit Structure: Interacts (via C-terminus) with FNIP1 and FNIP2 (via C-terminus). This mediates indirect interaction with the PRKAA1, PRKAB1 and PRKAG1 subunits of 5'-AMP-activated protein kinase (PubMed:17028174, PubMed:18403135, PubMed:18663353, PubMed:27353360). Interacts with HSP90AA1 in the presence of FNIP1. Interacts with HSP70, STUB1, CDC37, AHSA1, CCT2, STIP1, PTGES3 and PPP5C (PubMed:2 |
Immunogen | Immunogen: A synthesized peptide derived from human FLCN. Tissue Specificity: Expressed in most tissues tested, including skin, lung, kidney, heart, testis and stomach. |
Other Names | [BHD; BHD skin lesion fibrofolliculoma protein; Birt Hogg Dube syndrome protein; Birt-Hogg-Dube syndrome protein; DKFZp547A118; FLCL; Flcn; FLCN_HUMAN; FLJ45004; FLJ99377; Folliculin; MGC17998; MGC23445] |
Gene, Accession # | [FLCN], Gene ID: 201163, NCBI: NP_653207.1, UniProt: Q8NFG4 |
Catalog # | MBS9611360 |
Price | $240, $280 |
Order / More Info | FLCN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |