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Antigenic Specificity | Netrin-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Netrin-1 antibody detects endogenous levels of total Netrin-1. Function: Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.Subunit Structure: Binds to its receptors; DCC, DSCAM, UNC5A, UNC5B, UNC5C and probably UNC5D. |
Immunogen | Immunogen: A synthesized peptide derived from human Netrin-1 Subcellular Location: Extracellular Region or Secreted Tissue Specificity: Widely expressed in normal adult tissues with highest levels in heart, small intestine, colon, liver and prostate. Reduced expression in brain tumors and neuroblastomas. Expressed in epididymis (at protein level). Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Chicken, Xenopus Similarity: Pig (100%), Bovine (100%), Horse (90%), Sheep (100%), Chicken (90% |
Other Names | [epididymis tissue protein Li 131P; NET1_HUMAN; Netrin 1, mouse, homolog of; Netrin 1-like; Netrin-1; Netrin1; Ntn 1; NTN 1L; NTN1; NTN1L; Unc6] |
Gene, Accession # | [NTN1], Gene ID: 9423, NCBI: NP_004813.2, UniProt: O95631 |
Catalog # | MBS9608896 |
Price | $240, $280 |
Order / More Info | Netrin-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |