Human Cellular tumor antigen p53 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityHuman Cellular tumor antigen p53
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatcaprylic acid ammonium sulfate precipitate
Size0.05 mg, 0.1 mg
Concentrationn/a
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
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DescriptionActs as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and linc
ImmunogenImmunogen: Recombinant human Cellular tumor antigen p53 protein(2-393aa) Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-1314 / sc-1311-R / sc-6243
Other Names[Antigen NY-CO-13; Phosphoprotein p53; Tumor suppressor p53; TP53; P53], [TP53; TP53; P53; BCC7; LFS1; TRP53; P53]
Gene, Accession #Gene ID: 7157, NCBI: NP_000537.3, UniProt: P04637
Catalog #MBS1496692
Price$160, $235
Order / More InfoHuman Cellular tumor antigen p53 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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