Edit |   |
---|---|
Antigenic Specificity | CLN5 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plays a role in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. Regulates the localization and activation of RAB7A which is required to recruit the retromer complex to the endosomal membrane (PubMed:22431521). |
Immunogen | Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 96-407 of human CLN5 (NP 006484.1). |
Other Names | [ceroid-lipofuscinosis neuronal protein 5; Ceroid-lipofuscinosis neuronal protein 5; ceroid-lipofuscinosis neuronal protein 5; CLN5 intracellular trafficking protein] |
Gene, Accession # | [CLN5], Gene ID: 1203, NCBI: NP_006484.1, UniProt: O75503 |
Catalog # | MBS8548457 |
Price | $280 |
Order / More Info | CLN5 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |