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Antigenic Specificity | AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) |
Clone | [C2] |
Host Species | Mouse |
Reactive Species | human, mouse. does not react with cow, dog and rat |
Isotype | IgG1, kappa |
Format | unconjugated |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors. |
Immunogen | Immunogen: Alpha fetoprotein (AFP) purified from serum of a hepatoma patient |
Other Names | [Alpha fetoglobulin; FETA; HPAFP], [AFP; AFP; AFPD; FETA; HPAFP; HPAFP] |
Gene, Accession # | [AFP], Gene ID: 174, NCBI: NP_001125.1, UniProt: P02771 |
Catalog # | MBS438544 |
Price | $190, $340, $340 |
Order / More Info | AFP (Alpha Fetoprotein) (Hepatocellular/Germ Cell Tumor Marker) Antibody from MYBIOSOURCE INC. |
Product Specific References | Tsung K., et al.Milunsky A., Alpert E. Derivation and characterization of a monoclonal hybridoma antibody specific for human alpha-fetoprotein. J. Immunol. Methods 39: 363-368, (1980) Michell B., Fiebach H., Karsten U., Goussev A.I., Yazova A.K., Knopp J. Monoclonal antibodies to different epitopes of human alpha-fetoprotein (AFP). Eur. J. Cancer Clin. Oncol. 19:1239-1246, (1983). Yazova A.K., Goussev A.I., Poltorania V.S., Yakimenko E.F., Human alpha- fetoprotein epitopes as revealed by monoclonal antibodies. Immunol. Lett. 25: 325-330, (1990). Nustad K., Paus E., Kierulf B., Bormer O.P. Specificity and affinity of 30 monoclonal antibodies against alpha-fetoprotein. Tumor Biol 19: 293 -300, (1998). Yakimenko E.F., Karamova E.R., Goussev A.I., Hilgers J., Abelev G.I., Yazova A.K.: Epitope mapping of human alpha-fetoprotein. Tumor Biol 19: 301309, (1998) |