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Antigenic Specificity | RAIN |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of RAIN protein. Required for the proper formation of vascular structures that develop via both vasculogenesis and angiogenesis. Acts as a critical and vascular-specific regulator of GTPase signaling, cell architecture, and adhesion, which is essential for endothelial cell morphogenesis and blood vessel tubulogenesis. Regulates the activity of Rho GTPases in part by recruiting ARHGAP29 and suppressing RhoA signaling and dampening ROCK and MYH9 activities in endothelial cells. May act as effector for Golgi-bound HRAS and other Ras-like proteins. May promote HRAS-mediated transformation. Negative regulator of amino acid starvation-induced autophagy. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human RAIN protein at amino acid sequence of 620-700 |
Other Names | [Rabbit RAIN; Ras-interacting protein 1; Rain] |
Gene, Accession # | [RAIN], Gene ID: 54922, NCBI: NP_060275.2, UniProt: Q5U651 |
Catalog # | MBS9710624 |
Price | $130, $220, $325 |
Order / More Info | RAIN Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |