CD163 (N-term), 245-274 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | CD163 (N-term), 245-274 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | n/a |
| Applications | WB, IHC-P, E. |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This CD163 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-274 amino acids from the N-terminal region of human CD163. CD163 is an acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage. The protein may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. And it exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin |
| Immunogen | n/a |
| Other Names | [Scavenger receptor cysteine-rich type 1 protein M130; Hemoglobin scavenger receptor; CD163; Soluble CD163; sCD163; CD163; M130] |
| Gene, Accession # | [CD163], Gene ID: 9332, NCBI: NP_004235.4, UniProt: Q86VB7 |
| Catalog # | MBS9208646 |
| Price | $165, $370 |
| Order / More Info | CD163 (N-term), 245-274 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Buehler,P.W., Abraham,B. Blood 113 (11), 2578-2586 (2009) Fabriek,B.O., van Bruggen,R. Blood 113 (4), 887-892 (2009) Strauss,M. and Levy,A.P. Mol. Cell. Biochem. 317 (1-2), 131-135 (2008) Groselj-Grenc,M., Ihan,A. Mediators Inflamm. 2008, 202646 (2008) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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