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Antigenic Specificity | Che-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), Immunohistochemistry (IHC) Paraffin, ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Che-1 Polyclonal Antibody detects endogenous levels of Che-1 protein. Apoptosis antagonizing transcription factor encoded by AATF was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. AATF product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of AATF interfered with MAP3K12 induced apoptosis. |
Immunogen | Immunogen: Synthesized peptide derived from the N-terminal region of human Che-1 at AA range: 10-90 |
Other Names | [Rabbit Che-1; AATF; CHE1; DED; HSPC277; Protein AATF; Apoptosis-antagonizing transcription factor; Rb-binding protein Che-1] |
Gene, Accession # | [CHE-1], Gene ID: 26574, NCBI: NP_036270.1, UniProt: Q9NY61 |
Catalog # | MBS9701690 |
Price | $130, $220, $325 |
Order / More Info | Che-1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |