ADCY2 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityADCY2
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionSpecificity: ADCY2 antibody detects endogenous levels of total ADCY2. Function: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (By similarity).Subunit Structure: Interacts with RAF1 (PubMed:15385642). Interacts with GNAS. Interacts with the G protein beta and gamma subunit complex (By similarity).Post-translational Modifications: Phosphorylated by RAF1.Similarity: The protein contains two modules with six transmembrane helices each; both are required for catalytic activity.
ImmunogenImmunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Expressed in brain, especially in caudate nucleus, cerebellum and hippocampus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%)
Other Names[3', 5' cyclic AMP synthetase; Adenylate cyclase II; AC2; Adenylate cyclase 2 (brain); Adenylate cyclase 2; Adenylate cyclase type 2; Adenylate cyclase type II; ATP pyrophosphate lyase 2; FLJ16822; FLJ45092; HBAC2; KIAA1060; MGC133314; Type II adenylate cyclase]
Gene, Accession #[ADCY2], Gene ID: 108, NCBI: NP_065433.2, UniProt: Q08462
Catalog #MBS9603806
Price$240, $280
Order / More InfoADCY2 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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