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Antigenic Specificity | ADCY2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.1 mL, 0.2 mL |
Concentration | 1mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: ADCY2 antibody detects endogenous levels of total ADCY2. Function: Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling (PubMed:15385642). Down-stream signaling cascades mediate changes in gene expression patterns and lead to increased IL6 production. Functions in signaling cascades downstream of the muscarinic acetylcholine receptors (By similarity).Subunit Structure: Interacts with RAF1 (PubMed:15385642). Interacts with GNAS. Interacts with the G protein beta and gamma subunit complex (By similarity).Post-translational Modifications: Phosphorylated by RAF1.Similarity: The protein contains two modules with six transmembrane helices each; both are required for catalytic activity. |
Immunogen | Immunogen: A synthesized peptide Subcellular Location: Cell Membrane Tissue Specificity: Detected in zona glomerulosa and zona fasciculata in the adrenal gland (at protein level) (PubMed:11549699). Expressed in brain, especially in caudate nucleus, cerebellum and hippocampus. Predicted Cross Reactivity: Pig, Bovine, Horse, Sheep, Rabbit, Dog Similarity: Pig (92%), Bovine (100%), Horse (100%), Sheep (100%), Rabbit (100%), Dog (100%) |
Other Names | [3', 5' cyclic AMP synthetase; Adenylate cyclase II; AC2; Adenylate cyclase 2 (brain); Adenylate cyclase 2; Adenylate cyclase type 2; Adenylate cyclase type II; ATP pyrophosphate lyase 2; FLJ16822; FLJ45092; HBAC2; KIAA1060; MGC133314; Type II adenylate cyclase] |
Gene, Accession # | [ADCY2], Gene ID: 108, NCBI: NP_065433.2, UniProt: Q08462 |
Catalog # | MBS9603806 |
Price | $240, $280 |
Order / More Info | ADCY2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |