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Antigenic Specificity | Catenin gamma |
Clone | [1A5D10] |
Host Species | Mouse |
Reactive Species | human, rat |
Isotype | IgG1 |
Format | Protein G purified |
Size | 0.06 mL, 0.12 mL, 0.2 mL |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Plakoglobin (gamma-catenin), a member of the Armadillo proteins, plays important roles in cell adhesion with alpha-catenin and beta-catenin, is involved in Wnt signaling, and is translocated into the nucleus and binds LEF1. Plakoglobin is a major cytoplasmic component of both desmosomes and adherens junctions, and is the only known constituent common to submembranous plaques in both of these structures, which are located at the intercalated disc (ICD) of cardiomyocytes. Plakoglobin links cadherins to the actin cytoskeleton. Mutations in plakoglobin are associated with arrhythmogenic right ventricular dysplasia and Pemphigus vulgaris. |
Immunogen | Immunogen: Fusion protein of Plakoglobin/gamma catenin |
Other Names | [ARVD 12; ARVD12; Catenin (cadherin associated protein); gamma 80kDa; catenin (cadherin-associated protein) gamma (80kD); Catenin gamma; Desmoplakin 3; Desmoplakin III; Desmoplakin-3; Desmoplakin3; DesmoplakinIII; DP 3; DP III; DP3; DPIII; gamma catenin; Junction plakoglobin; JUP; OTTHUMP00000164732; OTTHUMP00000164735; OTTHUMP00000164738; PDGB; PKGB; PLAK; PLAKOGLOBIN] |
Gene, Accession # | [CTNNG], Gene ID: 3728, NCBI: NP_002221.1, UniProt: P14923 |
Catalog # | MBS2549125 |
Price | $220, $290, $435 |
Order / More Info | Catenin gamma Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |