PD-1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityPD-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry-Paraffin(IHC-P), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionPD-1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antig en-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PDL-1 and PDL-2. Upon binding to either of these ligands, signals generated by PD-1 inhibit the activation of the immune response in the absence of danger signals such as LPS or other molecules associated with bacteria or other pathogens. Evidence for this is seen in PD1-null mice who exhibit hyperactivated immune systems and autoimmune diseases
ImmunogenImmunogen: PD-1 antibody was raised against a 16 amino acid synthetic peptide from near the center of human PD-1. The Immunogen is located within amino acids 120-170 of PD-1. Buffer: PD-1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[PD-1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Programmed cell death protein 1; Protein PD-1; programmed cell death 1], [PDCD1; PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; PD1; Protein PD-1; hPD-1]
Gene, Accession #[PDCD1], Gene ID: 5133, NCBI: Q15116.3, UniProt: Q15116
Catalog #MBS150938
Price$375
Order / More InfoPD-1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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