SRPX1 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySRPX1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/mL
ApplicationsELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
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DescriptionSRPX1 Antibody: SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.
ImmunogenImmunogen: SRPX1 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human SRPX1. Buffer: SRPX1 Antibody is supplied in PBS containing 0.02% sodium azide.
Other Names[SRPX1; DRS; ETX1; SRPX1; HEL-S-83p; Sushi repeat-containing protein SRPX; sushi-repeat-containing protein, X-linked], [SRPX; SRPX; DRS; ETX1; SRPX1; HEL-S-83p; ETX1]
Gene, Accession #[SRPX], Gene ID: 8406, NCBI: NP_006298, UniProt: P78539
Catalog #MBS151426
Price$375
Order / More InfoSRPX1 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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