TICAM1 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | TICAM1 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | peptide affinity purified |
| Size | 0.1 mL, 0.2 mL |
| Concentration | 1mg/ml |
| Applications | Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: TICAM1 antibody detects endogenous levels of total TICAM1. Description: Members of the Toll-like receptor (TLR) family, named for the closely related Toll receptor in Drosophila, play a pivotal role in innate immune responses (1-3). TLRs recognize conserved motifs found in various pathogens and mediate defense responses. Triggering of the TLR pathway leads to the activation of NF-kappaB and subsequent regulation of immune and inflammatory genes. The TLRs and members of the IL-1 receptor family share a conserved stretch of approximately 200 amino acids known as the TIR domain. Upon activation, TLRs associate with a number of cytoplasmic adaptor proteins containing TIR domains including MyD88 (myeloid differentiation factor), MAL |
| Immunogen | Immunogen: A synthesized peptide derived from human TICAM1 Tissue Specificity: Ubiquitously expressed but with higher levels in liver. Predicted Cross Reactivity: Pig, Zebrafish, Bovine, Horse, Sheep, Dog, Chicken Similarity: Pig (100%), Zebrafish (88%), Bovine (100%), Horse (100%), Sheep (100%), Dog (100%), Chicken (100%) |
| Other Names | [IIAE6; MGC35334; MyD88 3; Proline rich vinculin and TIR domain containing protein B; Proline-rich; PRVTIRB; Putative NF kappa B activating protein 502H; Putative NF-kappa-B-activating protein 502H; Putative NFkB activating protein; TCAM1_HUMAN; TICAM 1; TICAM-1; Ticam1; TIR domain containing adapter molecule 1; TIR domain containing adapter protein inducing IFN beta; TIR domain containing adaptor inducing interferon beta; TIR domain-containing adapter molecule 1; TIR domain-containing adapter protein inducing IFN-beta; Toll interleukin 1 receptor domain containing adapter protein inducing interferon beta; Toll like receptor adaptor molecule 1; Toll-interleukin-1 receptor domain-containing adapter protein inducing interferon beta; TRIF; TRIF protein; vinculin and TIR domain-containing protein B] |
| Gene, Accession # | [TICAM1], Gene ID: 148022, NCBI: NP_891549.1, UniProt: Q8IUC6 |
| Catalog # | MBS9606948 |
| Price | $240, $280 |
| Order / More Info | TICAM1 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Yan Ding, Pan Liu, Zhi-Lin Chen, Shao-Jun Zhang, You-Qin Wang, Xin Cai, Lei Luo, Xuan Zhou and Lei Zhao; Journal: FRONT PHARMACOL. Emodin attenuates lipopolysaccharide-induced acute liver injury through inhibiting the TLR4 signalin. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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