KIDINS220 (C-term), 1518-1547 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityKIDINS220 (C-term), 1518-1547
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.08 mL, 0.4 mL
Concentrationvial concentration: 0.5
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionThis KIDINS220 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1518-1547 amino acids from the C-terminal region of human KIDINS220. KIDINS220 promotes a prolonged MAP-kinase signaling by neurotrophins through activation of a Rap1-dependent mechanism. Provides a docking site for the CRKL-C3G complex, resulting in Rap1-dependent sustained ERK activation. May play an important role in regulating postsynaptic signal transduction through the syntrophin-mediated localization of receptor tyrosine kinases such as EPHA4. In cooperation with SNTA1 can enhance EPHA4-induced JAK/STAT activation. May play a role in neurotrophin-and ephrin-mediated neuronal outgrowth and in axon guidance during neural developm
Immunogenn/a
Other Names[Kinase D-interacting substrate of 220 kDa; Ankyrin repeat-rich membrane-spanning protein; KIDINS220; ARMS; KIAA1250]
Gene, Accession #[KIDINS220], Gene ID: 57498, NCBI: NP_065789.1, UniProt: Q9ULH0
Catalog #MBS9213056
Price$165, $370
Order / More InfoKIDINS220 (C-term), 1518-1547 Antibody from MYBIOSOURCE INC.
Product Specific ReferencesWu, Z., et al. J. Biol. Chem. 283(42):28198-28215(2008) Sniderhan, L.F., et al. Mol. Cell. Neurosci. 38(3):404-416(2008) Li, J., et al. J. Biol. Chem. 283(5):2614-2621(2008) Liao, Y.H., et al. Cancer Res. 67(24):11547-11556(2007) Bracale, A., et al. Mol. Biol. Cell 18(1):142-152(2007)
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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