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Antigenic Specificity | Human CEACAM1,5,6,8 |
Clone | [TET2] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | Protein G purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Flow Cytometry (FC/FACS), CELISA, ELISA (EIA), Western Blot (WB), Immunohistology on cryosections |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: anti-human CEACAM1,5,6,8 (CD66a,b,c,e). Background: CEA-related cell adhesion molecules (CEACAM) belong to the carcinoembryonic antigen (CEA) family (1). The CEA family proteins belong to the immuno-globulin (Ig) superfamily and are composed of one Ig variable-like (IgV) and a varying number (0-6) of Ig constant-like (IgC) domains. CEACAM molecules are membrane-bound either via a transmembrane domain or a glycosyl phosphatidyl inositol (GPI) anchor. CEACAM molecules are differentially expressed in epithelial cells or in leucocytes. Over-expression of CEA/CEACAM5 in tumors of epithelial origin is the basis of its wide-spread use as a tumor marker (2). The function of CEACAM family members varies widely: they function as cell adh |
Immunogen | Immunogen: Immunogen: extracted protein of CEACAM5 |
Other Names | [CD66abce], [CEACAM1; CEACAM1; BGP; BGP1; BGPI; BGP; BGP1; BGP-1] |
Gene, Accession # | Gene ID: 634, NCBI: NP_001020083.1, UniProt: P13688 |
Catalog # | MBS468022 |
Price | $505 |
Order / More Info | Human CEACAM1,5,6,8 Antibody from MYBIOSOURCE INC. |
Product Specific References | Zimmermann W (2002). Carcinoembryonic antigen. In Wiley Encyclopedia of Molecular Medicine(T. Creighton, ed.), John Wiley & Sons Inc., New York, USA, pp. 459-462.Hammarstrom S (1999). The carcinoembryonic antigen (CEA) family: structures, suggestedfunctions and expression in normal and malignant tissues. Semin Cancer Biol 9, 67-81.Grunert F, AbuHarfeil N, Schwarz K and von Kleist S (1985). Two CEA and three NCAspecies, although distinguishable by monoclonal antibodies, have nearly identical peptidepatterns. Int J Cancer 36, 357-362.Grunert F, Stocks SC, Nagel G, Zimmermann W, Thompson JA, Jantscheff P and Kromer B(1996). CD66 family Workshop: Binding of myeloid blind panel antibodies and CD66 Subsectionantibodies to HeLa transfectants expressing individual CD66 molecules. In Leukocyte Typing VI:White cell Differentiation Antigens (T. Kishimoto et al., eds.), Garland Publishing Inc., New Yorkand London, pp. 1012-1025. |