SMAD3 (Center) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | SMAD3 (Center) |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | mouse, rat |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 0.5 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This SMAD3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 186-219 amino acids from the Central region of human SMAD3. Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD3/SMAD4 complex, activates transcription. Also can form a SMAD3/SMAD4/JUN/FOS complex at the AP-1/SMAD site to regulate TGF-beta-mediated transcription. Has an inhibitory effect on wound healing probably by modulating both growth and migration of primary keratinocytes and |
| Immunogen | n/a |
| Other Names | [Mothers against decapentaplegic homolog 3; MAD homolog 3; Mad3; Mothers against DPP homolog 3; hMAD-3; JV15-2; SMAD family member 3; SMAD 3; Smad3; hSMAD3; SMAD3; MADH3] |
| Gene, Accession # | [SMAD3], Gene ID: 4088, NCBI: NP_001138574.1, UniProt: P84022 |
| Catalog # | MBS9206822 |
| Price | $165, $370 |
| Order / More Info | SMAD3 (Center) Antibody from MYBIOSOURCE INC. |
| Product Specific References | Zhang Y.,et al.Nature 383:168-172(1996). Riggins G.J.,et al.Nat. Genet. 13:347-349(1996). Arai T.,et al.Cancer Lett. 122:157-163(1998). Hagiwara K.,et al.Submitted (SEP-1997) to the EMBL/GenBank/DDBJ databases. Ota T.,et al.Nat. Genet. 36:40-45(2004). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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