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Antigenic Specificity | CaVbeta4 |
Clone | [S10-7] |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG1 |
Format | ATTO 390 conjugate |
Size | 0.1 mg |
Concentration | 1mg/mL |
Applications | Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background Info: Detects ~50kDa. No cross-reactivity against rat Cab Beta1b, Cav beta2a, and Cav betas3 in transfected cells. Scientific Background: Ion channels are integral membrane proteins that help establish and control the small voltage gradient across the plasma membrane of living cells by allowing the flow of ions down their electrochemical gradient (1). They are present in the membranes that surround all biological cells because their main function is to regulate the flow of ions across this membrane. Whereas some ion channels permit the passage of ions based on charge, others conduct based on a ionic species, such as sodium or potassium. Furthermore, in some ion channels, the passage is governed by a gate which is controlled by ch |
Immunogen | n/a |
Other Names | [CAB4; CACNLB4; EA5; EJM; Calcium channel voltage dependent beta 4 subunit], [CACNB4; CACNB4; EA5; EJM; CAB4; EIG9; EJM4; EJM6; CACNLB4; CACNLB4; CAB4] |
Gene, Accession # | Gene ID: 785, NCBI: NP_000717.2, UniProt: O00305 |
Catalog # | MBS800085 |
Price | $440 |
Order / More Info | CaVbeta4 Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Hille B. (2001) Ion Channels of Excitable Membranes, 3rd Ed., Sinauer Associated Inc.: Sunderland, MA USA. 2. www.iochannels.org 3. Entrez Gene: CACNB4 calcium channel, voltage-dependent, beta 4 subunit 4. Xie M., et al. (2007) J Cell Biol. 178(3): 489-502. |