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Antigenic Specificity | HAVR2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 0.03 mL, 0.1 mL, 0.2 mL |
Concentration | 1 mg/ml |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The antibody detects endogenous levels of HAVR2 protein. The protein encoded by HAVCR2 belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance. |
Immunogen | Immunogen: Synthesized peptide derived from part region of human HAVR2 protein at amino acid sequence of 10-90 |
Other Names | [Rabbit HAVR2; T-cell immunoglobulin and mucin domain-containing protein 3; TIMD-3; T-cell immunoglobulin mucin receptor 3; TIM-3; T-cell membrane protein 3] |
Gene, Accession # | [HAVR2], Gene ID: 84868, NCBI: Q8TDQ0.3, UniProt: Q8TDQ0 |
Catalog # | MBS9709323 |
Price | $130, $220, $325 |
Order / More Info | HAVR2 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |