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Antigenic Specificity | DMRT1 (C-term), 296-322 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This DMRT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 296-322 amino acids from the C-terminal region of human DMRT1. This gene is found in a cluster with two other members ofthe gene family, having in common a zinc finger-like DNA-bindingmotif (DM domain). The DM domain is an ancient, conserved componentof the vertebrate sex-determining pathway that is also a keyregulator of male development in flies and nematodes. This geneexhibits a gonad-specific and sexually dimorphic expressionpattern. Defective testicular development and XY feminization occurwhen this gene is hemizygous. |
Immunogen | n/a |
Other Names | [Doublesex- and mab-3-related transcription factor 1; DM domain expressed in testis protein 1; DMRT1; DMT1] |
Gene, Accession # | [DMRT1], Gene ID: 1761, NCBI: NP_068770.2, UniProt: Q9Y5R6 |
Catalog # | MBS9202099 |
Price | $165, $370 |
Order / More Info | DMRT1 (C-term), 296-322 Antibody from MYBIOSOURCE INC. |
Product Specific References | Kang, J.U., et al. Int. J. Oncol. 37(2):327-335(2010) Turnbull, C., et al. Nat. Genet. 42(7):604-607(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Krentz, A.D., et al. Proc. Natl. Acad. Sci. U.S.A. 106(52):22323-22328(2009) Cheng, H.H., et al. Cell Res. 16(4):389-393(2006) |