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Antigenic Specificity | CD3e, Mouse |
Clone | [145-2C11] |
Host Species | Armenian Hamster |
Reactive Species | mousedoes not react with human. |
Isotype | IgG, kappa |
Format | purified |
Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
Concentration | n/a |
Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: CD3 chains. CD3 plays a critical role in TCR signal transduction, T cell activation, and antigen recognition by binding the peptide/MHC antigen complex. The 145-2C11 antibody is useful forin vitroblocking and activation assays, as well as apoptosis induction andin vivoT cell depletion. |
Immunogen | Immunogen: H2Kb specific Mouse cytotoxic T lymphocyte clone BM10 37 |
Other Names | [CD3 epsilon; CD3e; CD3e antigen epsilon polypeptide (TiT3 complex); CD3e molecule; epsilon (CD3-TCR complex); IMD18; T-cell surface antigen T3/Leu-4 epsilon chain; T-cell surface glycoprotein CD3 epsilon chain; T3E; TCRE] |
Gene, Accession # | [Cd3e], Gene ID: 12501, NCBI: NP_031674.1, UniProt: P22646 |
Catalog # | MBS4381454 |
Price | $190, $340, $340 |
Order / More Info | CD3e, Mouse Antibody from MYBIOSOURCE INC. |
Product Specific References | 1. Podd BS, et al. 2006. J. Immunol. 176:6532. (IHC). 2. Payer E, et al. 1991. J. Immunol. 146:2536. (IF). 3. Miescher GC, et al. 1989. Immunol. Lett. 23:113. (Block). 4. Wang W, et al. 2007. J. Immunol. 178:4885. (Activation). 5. Henrickson M, et al. 1995. Transplantation 60:828. (Deplete). 6. Salvadori S, et al. 1994. J. Immunol. 153:5176. (WB). 7. Leo O, et al. 1987. P. Natl. Acad. Sci. USA 84:1374. (IP, Activation) |