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Antigenic Specificity | PTPRC |
Clone | [5D3A3] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mL |
Concentration | n/a |
Applications | Western Blot (WB), Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Entrez Summary: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also su |
Immunogen | Immunogen: Purified recombinant fragment of human PTPRC (AA: 928-989) expressed in E Coli. |
Other Names | [LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180], [LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180] |
Gene, Accession # | [PTPRC], Gene ID: 5788, NCBI: AAH14239.1 |
Catalog # | MBS476495 |
Price | $335 |
Order / More Info | PTPRC Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |