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Antigenic Specificity | Apoptosis/Necroptosis Antibody Sampler Kit |
Clone | n/a |
Host Species | n/a |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | 1 kit |
Concentration | n/a |
Applications | Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Background: Apoptosis is a regulated physiological process leading to cell death. Caspases, a family of cysteine acid proteases, are central regulators of apoptosis. Caspases are synthesized as inactive zymogens containing a pro- domain followed by large (p20) and small subunits (p10) that are proteolytically processed in a cascade of caspase activity. Initiator caspases (including 8, 9, 10, and 12) are closely coupled to proapoptotic signals. Once activated, these caspases cleave and activate downstream effector caspases (including 3, 6, and 7), which in turn cleave cytoskeletal and nuclear proteins like PARP, alpha-fodrin, DFF, and lamin A, and induce apoptosis. Cytochrome c released from mitochondria is coupled to the activation of caspa |
Immunogen | n/a |
Other Names | [apoptosis-inducing factor 2; Apoptosis-inducing factor 2; apoptosis-inducing factor 2; apoptosis inducing factor, mitochondria associated 2; Apoptosis-inducing factor homologous mitochondrion-associated inducer of death; Apoptosis-inducing factor-like mitochondrion-associated inducer of death; p53-responsive gene 3 protein] |
Gene, Accession # | Gene ID: 84883, NCBI: NP_001185625.1, UniProt: Q9BRQ8 |
Catalog # | MBS2550011 |
Price | $345 |
Order / More Info | Apoptosis/Necroptosis Antibody Sampler Kit Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |