CRIM1 (CT) Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCRIM1 (CT)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), ELISA (EIA)
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DescriptionBackground: CRIM1 (cysteine-rich motor neuron 1), a glycosylated type I transmembrane protein, plays a role in tissue development i.e. capillary formation and maintenance during angiogenesis. It contains an N-terminal IGF-binding protein-like motif and six von Willebrand-like cysteine-rich repeats (CRRs) in its extracellular domain. CRIM1 interacts with BMP4 and BMP7 via the CRRs and functions as an antagonist. CRIM1 is developmentally expressed in a number of tissues including the pancreas, kidney, placenta, brain and blood vessels. CRIM1 may participate in CNS and placental development by interacting with growth factors involved in motor neuron differentiation and survival.
ImmunogenImmunogen: CRIM1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human Crim1. Positive Control: Western Blot: Jurkat cell lysate
Other Names[Cysteine rich transmembrane BMP regulator 1 (chordin-like); CRIM-1; Cysteine-rich motor neuron 1 protein; Cysteine-rich repeat-containing protein S52], [CRIM1; CRIM1; S52; CRIM-1; S52; CRIM-1]
Gene, Accession #[CRIM1], Gene ID: 51232, NCBI: NP_057525.1, UniProt: Q9NZV1
Catalog #MBS841101
Price$375
Order / More InfoCRIM1 (CT) Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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