TRAF-2 Antibody from MYBIOSOURCE INC.
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| Edit | |
|---|---|
| Antigenic Specificity | TRAF-2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | serum |
| Size | 0.05 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) Formalin/Paraffin, Immunoprecipitation (IP) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This antibody recognizes TRAF2, which is a member of TRAF (TNF receptor-associated factor) adapter proteins composed 501 amino acids. It Links TNFRs (TNF Receptors) to the SAPKs (Stress-Activated Protein Kinases) and p38s. TRAF2 can activate ASK1 (Apoptosis Signal-Regulating Kinase-1) in vivo and can interact in vivo with the amino- and carboxyl-terminal noncatalytic domains of the ASK1 polypeptide. Expression of the amino-terminal noncatalytic domain of ASK1 can inhibit TNF and TRAF2 activation of SAPK. TRAF2 is a potential mediator of CD40 signaling. In vitro, TRAF2 and TRAF3 bind to the CD40 Cytoplasmic Tail (CD40CT) with much higher affinity than TRAF5 and TRAF6 (TNF Receptor Associated Factor-6) and that TRAF2 and TRAF3 bind to differe |
| Immunogen | Immunogen Information: A synthetic peptide of human TRAF-2 (amino acids 87-106 SSSAFPDNAARREVESLPAV) was used as immunogen for this antibody |
| Other Names | [TRAF2; TRAP3; E3 ubiquitin-protein ligase TRAF2; Tumor necrosis factor type 2 receptor-associated protein 3; to TRAF-2; TRAF-2; TRAF-2], [TRAF2; TRAF2; TRAP; TRAP3; MGC:45012; TRAP3] |
| Gene, Accession # | [TRAF2], Gene ID: 7186, NCBI: Q12933.2, UniProt: Q12933 |
| Catalog # | MBS668814 |
| Price | $270 |
| Order / More Info | TRAF-2 Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
sales@mybiosource.com
http://www.MyBioSource.com
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