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Antigenic Specificity | CALR (Center), 277-305 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse (predicted reactivity: monkey) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This CALR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 277-305 amino acids from the Central region of human CALR. Calreticulin is a multifunctional protein that acts as a major Ca(2+)-binding (storage) protein in the lumen of the endoplasmic reticulum. It is also found in the nucleus, suggesting that it may have a role in transcription regulation. Calreticulin binds to the synthetic peptide KLGFFKR, which is almost identical to an amino acid sequence in the DNA-binding domain of the superfamily of nuclear receptors. Calreticulin binds to antibodies in certain sera of systemic lupus and Sjogren patients which contain anti-Ro/SSA antibodies, it is highly conserved among species, and it is locate |
Immunogen | n/a |
Other Names | [Calreticulin; CRP55; Calregulin; Endoplasmic reticulum resident protein 60; ERp60; HACBP; grp60; CALR; CRTC] |
Gene, Accession # | [CALR], Gene ID: 811, NCBI: NP_004334.1, UniProt: P27797 |
Catalog # | MBS9202793 |
Price | $165, $370 |
Order / More Info | CALR (Center), 277-305 Antibody from MYBIOSOURCE INC. |
Product Specific References | Alur,M., et.al., Am. J. Pathol. 175 (2), 882-890 (2009) |