SMAD6 Antibody from MYBIOSOURCE INC.

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Antigenic SpecificitySMAD6
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formataffinity purified
Size0.1 mL
Concentrationn/a
ApplicationsWestern Blot (WB), Immunohistochemistry (IHC)
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DescriptionActs as a mediator of TGF-beta and BMP antiflammatory activity. Suppresses IL1R-TLR signaling through its direct interaction with PEL1, preventing NF-kappa-B activation, nuclear transport and NF-kappa-B-mediated expression of proinflammatory genes. May block the BMP-SMAD1 signaling pathway by competing with SMAD4 for receptor-activated SMAD1-binding. Binds to regulatory elements in target promoter regions.
ImmunogenImmunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 257-496 of human SMAD6 (NP 005576.3).
Other Names[AOVD2; MADH6; MADH7; HsT17432]
Gene, Accession #[SMAD6], Gene ID: 4091, NCBI: O43541.2, UniProt: O43541
Catalog #MBS8549588
Price$280
Order / More InfoSMAD6 Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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