CEMIP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCEMIP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse
Isotypen/a
Formatantigen affinity purified
Size0.1 mL
Concentration1.7 mg/mL
ApplicationsImmunohistochemistry (IHC)
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DescriptionThe antibody detects endogenous levels of total CEMIP protein. Mediates depolymerization of hyaluronic acid (HA) via the cell membrane-associated clathrin-coated pit endocytic pathway. Binds to hyaluronic acid. Hydrolyzes high molecular weight hyaluronic acid to produce an intermediate-sized product, a process that may occur through rapid vesicle endocytosis and recycling without intracytoplasmic accumulation or digestion in lysosomes. Involved in hyaluronan catabolism in the dermis of the skin and arthritic synovium. Positively regulates epithelial-mesenchymal transition (EMT), and hence tumor cell growth, invasion and cancer dissemination. In collaboration with HSPA5/BIP, promotes cancer cell migration in a calcium and PKC-dependent manne
ImmunogenImmunogen: Synthetic peptide of human CEMIP Immunogen Type: Peptide
Other Names[CCSP1; HYBID; TMEM2L; KIAA1199]
Gene, Accession #[CEMIP], Gene ID: 57214, NCBI: NP_001280227.1, UniProt: Q8WUJ3
Catalog #MBS9430675
Price$255
Order / More InfoCEMIP Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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