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Antigenic Specificity | PIG CD18a |
Clone | [PNK-I] |
Host Species | Mouse |
Reactive Species | n/a |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 0.1 mg |
Concentration | IgG concentration 0.1 mg/ml |
Applications | Flow cytometry (FC/FACS) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti Pig CD18a, clone PNK-I recognizes porcine CD18a. PNK-I was clustered as CD18a at the Second International Workshop to Define Swine Cluster of Differentiation (CD) Antigens (Saalmuller et al. 1998). Clone PNK-I immunoprecipitates proteins of ~166kDa, ~155kDa and ~95 kDa under non-reducing conditions, specifically recognizing the 95kDa protein, consistent with the integrin beta2 chain (CD18). PNK-I inhibits porcine NK cell activity independent of any effect on antibody dependent cellular cytotoxicity (Dato and Kim 1990). CD18 is a single pass type I transmembrane protein and is expressed on all leukocytes and is involved in a variety of cell functions. CD18 acts as a receptor for several ICAM molecules effecting intercellular adhes |
Immunogen | n/a |
Other Names | [integrin beta-2; Integrin beta-2; integrin beta-2; CD18 leukocyte adhesion molecule; cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; complement receptor C3 subunit beta; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; CD_antigen: CD18], [ITGB2; ITGB2; CD18; CD18] |
Gene, Accession # | [CD18a], Gene ID: 396943, NCBI: NP_999073.1, UniProt: P53714 |
Catalog # | MBS210820 |
Price | $560 |
Order / More Info | PIG CD18a Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |