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Antigenic Specificity | Phospho-ILK (S246) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, mouse, rat) |
Isotype | n/a |
Format | peptide affinity purified |
Size | 0.08 mL, 0.4 mL |
Concentration | n/a |
Applications | Dot Blot (DB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This ILK Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S246 of human ILK. Transduction of extracellular matrix signals through integrins influences intracellular and extracellular functions, and appears to require interaction of integrin cytoplasmic domains with cellular proteins. Integrin-linked kinase (ILK), interacts with the cytoplasmic domain of beta-1 integrin. ILK is a serine/threonine protein kinase with 4 ankyrin-like repeats, which associates with the cytoplasmic domain of beta integrins and acts as a proximal receptor kinase regulating integrin-mediated signal transduction. |
Immunogen | n/a |
Other Names | [Integrin-linked protein kinase; 59 kDa serine/threonine-protein kinase; ILK-1; ILK-2; p59ILK; ILK; ILK1; ILK2] |
Gene, Accession # | [ILK], Gene ID: 3611, NCBI: NP_001014794.1, UniProt: Q13418 |
Catalog # | MBS9202503 |
Price | $165, $370 |
Order / More Info | Phospho-ILK (S246) Antibody from MYBIOSOURCE INC. |
Product Specific References | Li, Y., et al., J. Clin. Invest. 112(4):503-516 (2003). Troussard, A.A., et al., J. Biol. Chem. 278(25):22374-22378 (2003). Marotta, A., et al., Br. J. Cancer 88(11):1755-1762 (2003). Cordes, N., et al., Br. J. Cancer 88(9):1470-1479 (2003). Fukuda, T., et al., J. Cell Biol. 160(7):1001-1008 (2003). |