Edit |   |
---|---|
Antigenic Specificity | Human RHOB |
Clone | [2916C2a] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | unconjugated |
Size | 0.1 mg |
Concentration | 100 ug/ml (1.0 ml) |
Applications | Dot Blot (DB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development. [UniProtKB Function] |
Immunogen | n/a |
Other Names | [Homo sapiens ras homolog gene family, member B (RHOB); ARH6;ARHB; RHOH6; MST081; MSTP081], [RHOB; RHOB; ARH6; ARHB; RHOH6; MST081; MSTP081] |
Gene, Accession # | [RHOB], Gene ID: 388, NCBI: NP_004031.1 |
Catalog # | MBS120245 |
Price | $395 |
Order / More Info | Human RHOB Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |