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Antigenic Specificity | ARF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | Protein G purified |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | ELISA (EIA), Immunohistochemistry (IHC), Immunofluorescence (IF) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Involved in protein trafficking among different compartments. Modulates vesicle budding and uncoating within the Golgi complex. Deactivation induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, suggesting a crucial role in protein trafficking. In its GTP-bound form, its triggers the association with coat proteins with the Golgi membrane. The hydrolysis of ARF1-bound GTP, which is mediated by ARFGAPs proteins, is required for dissociation of coat proteins from Golgi membranes and vesicles. The GTP-bound form interacts with PICK1 to limit PICK1-mediated inhibition of Arp2/3 complex ac |
Immunogen | Immunogen: Recombinant Human ADP-ribosylation factor 1 protein (2-181AA) Conjugation: Non-conjugated |
Other Names | [ADP-ribosylation factor 1; ARF1] |
Gene, Accession # | [ARF1], Gene ID: 375, NCBI: NP_001019397.1, UniProt: P84077 |
Catalog # | MBS7051969 |
Price | $160, $235 |
Order / More Info | ARF1 Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |