Human CD275 (ICOSL, GL50, B7-H2) Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | Human CD275 (ICOSL, GL50, B7-H2) |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | human |
| Isotype | IgG1k |
| Format | unconjugated |
| Size | 0.1 mL |
| Concentration | 1ug/ul |
| Applications | n/a |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: Antibody ANC4E3 binds to recombinant CD275 in EIA. mAb name/clone: ANC4E3The inducible costimulator (ICOS, CD278) is similar to human CD28 (24% homology), and plays an analogous role in the T cell activation process. Unlike CD28, ICOS is only expressed on activated T cells. Secondary signaling through CD28 or ICOS results in discrete cytokine secretion profiles by the activated T cells(1). Engagement of CD152 (CTLA-4) anergizes cells costimulated with either CD28 and ICOS(2). Signaling through ICOS is particularly important in progression of TH2 immune response (5). The receptor for human ICOS is GL50(ICOS L), a member of the B7 family sharing ~20% homology with CD80 (B7-1) and CD86 (B7-2)(3). Two RNA splice variants exist for |
| Immunogen | Immunogen: Human Raji cells, recombinant human CD275-muIg |
| Other Names | n/a |
| Gene, Accession # | [CD275] |
| Catalog # | MBS4159610 |
| Price | $540 |
| Order / More Info | Human CD275 (ICOSL, GL50, B7-H2) Antibody from MYBIOSOURCE INC. |
| Product Specific References | n/a |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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http://www.MyBioSource.com
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