CIRBP Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityCIRBP
Clone[1C9]
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG2a,k
FormatProtein A purified
Size0.1 mg
Concentration1.0mg/ml
ApplicationsELISA (EL/EIA), Western Blot (WB)
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DescriptionRecognizes human CIRBP. Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed.
ImmunogenImmunogen: Partial recombinant corresponding to aa1-90 from human CIRBP (NP 001271.1) with GST tag. MW of the GST tag alone is 26kD.
Other NamesCIRBP (Cold-inducible RNA-binding Protein, A18 hnRNP, Glycine-rich RNA-binding Protein CIRP, A18HNRNP, CIRP)
Gene, Accession #Gene ID: 1153, NCBI: NP_001271.1, UniProt: Q14011
Catalog #MBS6007311
Price$580
Order / More InfoCIRBP Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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