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Antigenic Specificity | CIRBP |
Clone | [1C9] |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a,k |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | 1.0mg/ml |
Applications | ELISA (EL/EIA), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recognizes human CIRBP. Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor. Promotes assembly of stress granules (SGs), when overexpressed. |
Immunogen | Immunogen: Partial recombinant corresponding to aa1-90 from human CIRBP (NP 001271.1) with GST tag. MW of the GST tag alone is 26kD. |
Other Names | CIRBP (Cold-inducible RNA-binding Protein, A18 hnRNP, Glycine-rich RNA-binding Protein CIRP, A18HNRNP, CIRP) |
Gene, Accession # | Gene ID: 1153, NCBI: NP_001271.1, UniProt: Q14011 |
Catalog # | MBS6007311 |
Price | $580 |
Order / More Info | CIRBP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |