PAD4 (C-term), 512-544 Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | PAD4 (C-term), 512-544 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | purified |
| Size | 0.08 mL, 0.4 mL |
| Concentration | vial concentration: 2 |
| Applications | Western Blot (WB), ELISA (EIA) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | This PAD4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 512-544 amino acids from the C-terminal region of human PAD4. PAD4 is a member of a family of enzymes responsible for the conversion of arginine residues to citrulline residues via catalyzation of the deimination of the arginine residues. PAD4 down-regulates histone H3 and H4 arginine methylation, both by preventing arginine methylation by CARM1 and HRMT1L2/PRMT1 and by converting methylarginine to citrulline. This protein may play a role in granulocyte and macrophage development leading to inflammation and immune response. |
| Immunogen | n/a |
| Other Names | [Protein-arginine deiminase type-4; HL-60 PAD; Peptidylarginine deiminase IV; Protein-arginine deiminase type IV; PADI4; PADI5; PDI5] |
| Gene, Accession # | [PADI4], Gene ID: 23569, NCBI: NP_036519.2, UniProt: Q9UM07 |
| Catalog # | MBS9201969 |
| Price | $165, $370 |
| Order / More Info | PAD4 (C-term), 512-544 Antibody from MYBIOSOURCE INC. |
| Product Specific References | Nakayama-Hamada, M., et al., Biochem. Biophys. Res. Commun. 327(1):192-200 (2005). Wang, Y., et al., Science 306(5694):279-283 (2004). Arita, K., et al., Arthritis Rheum. 11(8):777-783 (2004). Barton, A., et al., Arthritis Rheum. 50(4):1117-1121 (2004). Suzuki, A., et al., Nat. Genet. 34(4):395-402 (2003). |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
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