NrCAM Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityNrCAM
Clone[S364-51]
Host SpeciesMouse
Reactive Specieshuman, mouse, rat
IsotypeIgG2a
FormatAPC-Cy7 conjugate
Size0.1 mg
Concentration1 mg/ml
ApplicationsWestern Blot (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)
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DescriptionDetects ~160 kDa. Neuronal cell adhesion molecule (NrCAM) is a cell surface protein of the immunoglobulin (Ig) superfamily. NrCAM (also known as Bravo) contains six Ig domains, five fibronectin repeats, a transmembrane region and an intracellular domain. NrCAM is expressed in brain, spinal cord, peripheral nervous system and pancreas. In the spinal cord, NrCAM acts as a ligand for axonin-1 to guide commissural axons across the floor plate. NrCAM also acts as a ligand for F3 to control actin-dependent growth cone motility. NrCAM interacts with neurofascin and may facilitate the clustering of the cystoskeletal protein ankyrin G and the voltage-dependent sodium channel proteins at the node of Ranvier. NrCAM expression may play a role in the se
ImmunogenImmunogen: Fusion protein amino acids 30-845 (extracellular domain) of mouse NrCAM. Rat: 96% identity (795/822 amino acids identical). Human: 91% identity (753/822 amino acids identical) ~50% identity with Neurofascin.
Other Names[Mouse Mouse NrCAM IgG2a; NrCAM : APC/Cy7; Neuronal cell adhesion molecule; Bravo; hBravo; KIAA0343; MGC138845; MGC138846; Neuronal surface protein Bravo; Ng CAM related; Ng-CAM-related; NgCAM related cell adhesion molecule; NgCAM-related cell adhesion molecule; Nr CAM; Nr-CAM]
Gene, Accession #[NrCAM], Gene ID: 319504, NCBI: NP_001139503.1, UniProt: Q810U4
Catalog #MBS8003454
Price$510
Order / More InfoNrCAM Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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