DNMT3a Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityDNMT3a
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formataffinity purified
Size0.03 mg, 0.1 mg
Concentration0.5 mg/ml
ApplicationsWestern Blot (WB)
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DescriptionPolyclonal Antibody to detect DNMT3a in human, mouse and rat samples. Background: Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting, and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, three families of mammalian DNA methyltransferase genes have been identified which include DNMT1, DNMT2, and DNMT3. DNMT1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality. DNMT2 is expressed at low levels in adult tissues and its inactivation does not affect
ImmunogenImmunogen: Synthetic peptide at near N-terminal. Positive Control: Western blot: Jurket cell lysate
Other Names[DNA Methyltransferase 3a; DNMT3A], [DNMT3A; Dnmt3a; DNA MTase HsaIIIA; M.HsaIIIA]
Gene, Accession #[DNMT3a], Gene ID: 1788, NCBI: NP_072046.2, UniProt: Q9Y6K1
Catalog #MBS840657
Price$150, $325
Order / More InfoDNMT3a Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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