TRAF6 Antibody from MYBIOSOURCE INC.
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|---|---|
| Antigenic Specificity | TRAF6 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | affinity purified |
| Size | 0.1 mL |
| Concentration | n/a |
| Applications | Western Blot (WB), Immunohistochemistry (IHC) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | TRAFs (TNF receptor-associated factors) are a family of multifunctional adaptor proteins that bind to surface receptors and recruit additional proteins to form multiprotein signaling complexes capable of promoting cellular responses (1-3). Members of the TRAF family share a common carboxy-terminal TRAF domain which mediates interactions with associated proteins; many also contain amino-terminal Zinc/RING finger motifs. The first TRAFs identified, TRAF1 and TRAF2, were found by virtue of their interactions with the cytoplasmic domain of TNF-receptor 2 (TNFRII) (4). The six known TRAFs (TRAF1-6) act as adaptor proteins for a wide range of cell surface receptors and participate in the regulation of cell survival, proliferation, differentiati |
| Immunogen | Immunogen: Recombinant protein of human TRAF6 Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Other Names | [TRAF6; MGC:3310; RNF85] |
| Gene, Accession # | [TRAF6], Gene ID: 7189, NCBI: NP_004611.1, UniProt: Q9Y4K3 |
| Catalog # | MBS8502526 |
| Price | $310 |
| Order / More Info | TRAF6 Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Arch, R.H. et al. (1998) Genes Dev. 12, 2821-2830. 2. Chung, J. Y. et al. (2002) J. Cell Sci. 115, 679-688. 3. Bradley, J.R. and Pober, J.S. (2001) Oncogene 20, 6482-6491. 4. Rothe, M. et al. (1994) Cell 78, 681-692. 5. Wu, H. and Arron, J.R. (2003) Bioessays 25, 1096-105. 6. Lomaga, M.A. et al. (1999) Genes Dev 13, 1015-24. 7. Lomaga, M.A. et al. (2000) J Neurosci 20, 7384-93. 8. Ye, H. et al. (2002) Nature 418, 443-7. 9. Cao, Z. et al. (1996) Nature 383, 443-6. 10. Muzio, M. et al. (1997) Science 278, 1612-5. 11. Medzhitov, R. et al. (1998) Mol Cell 2, 253-8. 12. Ishida, T. et al. (1996) J Biol Chem 271, 28745-8. 13. Darnay, B.G. et al. (1998) J Biol Chem 273, 20551-5. 14. Wong, B.R. et al. (1998) J Biol Chem 273, 28355-9. 15. Khursigara, G. et al. (1999) J Biol Chem 274, 2597-600. 16. Ninomiya-Tsuji, J. et al. (1999) Nature 398, 252-6. 17. Wong, B.R. et al. (1999) Mol Cell 4, 1041-9. |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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