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Antigenic Specificity | PAX6 (Center) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human (predicted reactivity: bovine, zebrafish, mouse) |
Isotype | n/a |
Format | purified |
Size | 0.08 mL, 0.4 mL |
Concentration | vial concentration: 0.5 |
Applications | Western Blot (WB), ELISA (EIA) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This PAX6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 183-214 amino acids from the Central region of human PAX6. Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes. |
Immunogen | n/a |
Other Names | [Paired box protein Pax-6; Aniridia type II protein; Oculorhombin; PAX6; AN2] |
Gene, Accession # | [PAX6], Gene ID: 5080, NCBI: NP_000271.1, UniProt: P26367 |
Catalog # | MBS9203936 |
Price | $165, $370 |
Order / More Info | PAX6 (Center) Antibody from MYBIOSOURCE INC. |
Product Specific References | Ton C.C.T.,et al.Cell 67:1059-1074(1991). Glaser T.,et al.Nat. Genet. 2:232-239(1992). Liu J.,et al.Submitted (JUL-2001) to the EMBL/GenBank/DDBJ databases. Bechtel S.,et al.BMC Genomics 8:399-399(2007). Taylor T.D.,et al.Nature 440:497-500(2006). |