NK1.1/CD161c/Klrb1c, Mouse Antibody from MYBIOSOURCE INC.
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| Antigenic Specificity | NK1.1/CD161c/Klrb1c, Mouse |
| Clone | [PK136] |
| Host Species | Mouse |
| Reactive Species | mousedoes not react with human. |
| Isotype | IgG2a, kappa |
| Format | purified |
| Size | 0.02 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (With BSA & Azide at 0.2mg/ml), 0.1 mg (Without BSA & Azide at 1mg/ml) |
| Concentration | n/a |
| Applications | Functional Studies, Flow Cytometry (FC/FACS), Immunofluorescence (IF) |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Specificity: NK1.1 is a type II integral membrane glycoprotein with a C-type lectin domain and is encoded by theKlrb1c/NKR-P1Cgene.It is predominantly expressed as a disulfide-linked homodimer on NK cells however; it is also expressed on NK-T cells, a rare population of T lymphocytes.NK1.1 is expressed in some Mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cellsin vitroand rejection of bone marrow allograftsin vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN- production, and cytotoxic granule release. NK-1.1 is commonly used as a Mouse NK cell marker. |
| Immunogen | Immunogen: CD Mouse spleen and bone marrow cells enriched for NK-1 cells |
| Other Names | [CD161 antigen-like family member C; CD161c; Killer cell lectin-like receptor subfamily B member 1C (Klrb1c); Klrb1f; Lymphocyte antigen 55c (Ly55c); Lymphocyte antigen 59; Natural killer cell surface protein P1-40; NK1.1; NKR-P1 40; NKR-P1.9; NKR-P1C; NKRP1] |
| Gene, Accession # | [Klrb1c], Gene ID: 17059, NCBI: NP_001153376.1, UniProt: P27814 |
| Catalog # | MBS4381468 |
| Price | $190, $340, $340 |
| Order / More Info | NK1.1/CD161c/Klrb1c, Mouse Antibody from MYBIOSOURCE INC. |
| Product Specific References | 1. Bankoti J, et al. 2010. Toxicol. Sci. 115:422. (FC). 2. Kanwar JR, et al. 2001. J. Natl. Cancer Inst. 93:1541. (IHC, IF). 3. Sentman CL, et al. 1989. Hybridoma 8:605. (IP). 4. Drobyski W, et al. 1996. Blood 87:5355. (Deplete). 5. Kung SK, et al. 1999. J. Immunol. 162:5876. (Block) |
MYBIOSOURCE INC.
MYBIOSOURCE INC.
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San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166
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