GC Antibody from MYBIOSOURCE INC.

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Antigenic SpecificityGC
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size0.1 mL, 0.2 mL
Concentration1mg/ml
ApplicationsWestern Blot (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), ELISA (EIA)
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DescriptionSpecificity: GC antibody detects endogenous levels of total GC. Function: Involved in vitamin D transport and storage, scavenging of extracellular G-actin, enhancement of the chemotactic activity of C5 alpha for neutrophils in inflammation and macrophage activation.Subunit Structure: Associates with membrane-bound immunoglobulin on the surface of B-lymphocytes and with IgG Fc receptor on the membranes of T-lymphocytes. Interacts with LRP2; the interaction is required for renal uptake of GC in complex with 25-hydroxyvitamin D3 (By similarity).Post-translational Modifications: Allele GC*1S is O-glycosylated at Thr-436 (PubMed:20079467). The trisaccharide sugar moiety can be modified by the successive removal of neuraminic acid and gal
ImmunogenImmunogen: A synthesized peptide derived from human GC Subcellular Location: Secreted. Tissue Specificity: Expressed in the liver. Found in plasma, ascites, cerebrospinal fluid and urine. Predicted Cross Reactivity: Bovine, Horse, Sheep Similarity: Bovine (82%), Horse (91%), Sheep (91%)
Other Names[DBP; DBP/GC; GC; Gc globulin; Gc-globulin; GRD3; Group specific component; Group specific component vitamin D binding protein; Group-specific component; hDBP; VDB; VDBG; VDBP; Vitamin D binding alpha globulin; Vitamin D-binding protein; VTDB_HUMAN]
Gene, Accession #[GC], Gene ID: 2638, NCBI: NP_000574.2, UniProt: P02774
Catalog #MBS9608389
Price$240, $280
Order / More InfoGC Antibody from MYBIOSOURCE INC.
Product Specific Referencesn/a
MYBIOSOURCE INC.
MYBIOSOURCE INC.
MYBIOSOURCE INC.
P.O. Box 153308
San Diego CA 92195-3308
P: 1.858.633.0165
P: 1.888.MBS.0165 (1.888.627.0165) (US & Canada)
F: 1.858.633.0166

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