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Antigenic Specificity | IKAP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mousepredicted: rat |
Isotype | n/a |
Format | biotin conjugate |
Size | 0.1 mg |
Concentration | 0.5 ug/ul in antibody stabilization buffer |
Applications | ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Overview: May act as a scaffold protein that may assemble active IKK-MAP3K14 complexes (IKKA, IKKB and MAP3K14/NIK). Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. Involved in neurogenesis (PubMed:19185337). Regulates the migration and branching of projection neurons in the developing cerebral cortex, through a process depending on alpha-tubulin acetylation (PubMed:19185337).Expression: Widely expressed with highest levels in brain. |
Immunogen | Immunogen: Synthetic peptide taken within amino acid region 1280-1330 on mouse Elongator Complex Protein 1. Conjugation: BIOTIN |
Other Names | [BIOTIN-Conjugated Elongator complex protein 1; DYS; Dysautonomia (Riley Day syndrome hereditary sensory autonomic neuropathy type III); Elongator complex protein 1; ELP1; FD; IKAP; IkappaB kinase complex associated protein; ikbkap; IKI3; IKK complex associated protein; Inhibitor of kappa light polypeptide gene enhancer in B cells kinase complex associated protein; p150; TOT1] |
Gene, Accession # | [IKAP], Gene ID: 230233, NCBI: NP_080355.2, UniProt: Q7TT37 |
Catalog # | MBS5400442 |
Price | $495 |
Order / More Info | IKAP Antibody from MYBIOSOURCE INC. |
Product Specific References | n/a |